Clinical Interventions in Aging (Oct 2023)

Procedural Intervention for Benign Prostatic Hyperplasia in Men ≥ Age 70 Years – A Review of Published Literature

  • Codelia-Anjum AJ,
  • Berjaoui MB,
  • Khondker A,
  • Elterman D,
  • Zorn KC,
  • Bhojani N,
  • Lerner LB,
  • Chughtai B

Journal volume & issue
Vol. Volume 18
pp. 1705 – 1717

Abstract

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Alia J Codelia-Anjum,1,* Mohamad Baker Berjaoui,2,* Adree Khondker,2 Dean Elterman,2 Kevin C Zorn,3 Naeem Bhojani,3 Lori B Lerner,4 Bilal Chughtai1 1Department of Urology, Weill Cornell Medical College/New York Presbyterian, New York, NY, USA; 2Division of Urology, Department of Surgery, University Health Network, University of Toronto, Toronto, ON, Canada; 3Division of Urology, Centre Hospitalier de l’Université de Montréal, Montreal, QC, Canada; 4Department of Urology, VA Boston Healthcare System, Boston, MA, USA*These authors contributed equally to this workCorrespondence: Bilal Chughtai, Weill Cornell Medical Center, Department of Urology, 425 East 61st Street, 12th Floor, New York, NY, 10065, USA, Tel +1 646 962-4811, Email [email protected]: We set out to review studies reporting on the use of surgical intervention to treat Benign Prostatic Hyperplasia in elderly men ≥ 70 years of age.Methods: A systematic literature search was conducted using Scopus, PubMed-MEDLINE, Cochrane, and Wiley Online Library databases including studies published between January 2012 through December 2022. This 10-year interval was chosen given the recent plethora of new modalities that have entered the BPH armamentarium, many of which have been marketed as appropriate for older and high-risk patients. The following database search words were used either individually or in conjunction: “BPH”, “elderly”, “surgical”, “ablation”, “resection”, “embolization”, and “aging”.Results: We identified 28 studies for inclusion in this review. The pros and cons of these modalities are presented, specifically as applicable to an older and higher risk population.Conclusion: There are a wide variety of surgical procedures available for surgically treating BPH in elderly men with varying states of health. Each of these comes with different risks and benefits, supporting that individualized approaches are important. Long-term data and further studies comparing modalities, specifically as regards the elderly and frail, would enhance our approaches to BPH treatment in this patient population.Keywords: benign prostatic hyperplasia, aging, elderly, surgical

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