Clinical Case Reports (Jan 2022)

Combined large cell neuroendocrine carcinoma and squamous cell carcinoma of the oropharynx: A collision course of tumors

  • Nicholas A. Rossi,
  • Rachelle Gietzen,
  • Lauren T. Malaya,
  • Kareem B. Haroun,
  • Grant R. Conner,
  • Orly Coblens,
  • Vicente A. Resto,
  • Cecilia G. Clement,
  • Rohan Joshi

DOI
https://doi.org/10.1002/ccr3.5319
Journal volume & issue
Vol. 10, no. 1
pp. n/a – n/a

Abstract

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Abstract Combined large cell neuroendocrine carcinoma (LCNEC) and squamous cell carcinoma (SCC) of the H&N are exceptionally rare. We present the case of combined p16 negative SCC and LCNEC of the oropharynx treated with combination chemotherapy. This is the third reported case of combined neuroendocrine carcinoma and SCC of the oropharynx.

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