mBio (Jun 2021)

Genetic Variation in PFKFB3 Impairs Antifungal Immunometabolic Responses and Predisposes to Invasive Pulmonary Aspergillosis

  • Samuel M. Gonçalves,
  • Daniela Antunes,
  • Luis Leite,
  • Toine Mercier,
  • Rob ter Horst,
  • Joana Vieira,
  • Eduardo Espada,
  • Carlos Pinho Vaz,
  • Rosa Branca,
  • Fernando Campilho,
  • Fátima Freitas,
  • Dário Ligeiro,
  • António Marques,
  • Frank L. van de Veerdonk,
  • Leo A. B. Joosten,
  • Katrien Lagrou,
  • Johan Maertens,
  • Mihai G. Netea,
  • João F. Lacerda,
  • António Campos,
  • Cristina Cunha,
  • Agostinho Carvalho

DOI
https://doi.org/10.1128/mBio.00369-21
Journal volume & issue
Vol. 12, no. 3

Abstract

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The fungal pathogen Aspergillus fumigatus