208 RTX-224, an engineered allogeneic red cell therapeutic expressing 4–1BBL and IL-12, activates immune cells in blood and spleen to promote tumor growth inhibition in mice

• Sivan Elloul,
• Anne-Sophie Dugast,
• Shannon McArdel,
• Enping Hong,
• Maegan Hoover,
• Laurence Turka,
• Zafira Castano,
• Arjun Reddy Bollampalli,
• Shannon Leonard,
• Ryan Pepi,
• Alex Nanna

Affiliations

Sivan Elloul

Aff6 grid.417407.1Karyopharm Therapeutics Newton MA USA

Anne-Sophie Dugast

Rubius Therapeutics, Cambridge, MA, USA

Shannon McArdel

Rubius Therapeutics, Cambridge, MA, USA

Enping Hong

Rubius Therapeutics, Cambridge, MA, USA

Maegan Hoover

Rubius Therapeutics, Cambridge, MA, USA

Laurence Turka

Rubius Therapeutics, Cambridge, MA, USA

Zafira Castano

Rubius Therapeutics, Cambridge, MA, USA

Arjun Reddy Bollampalli

Rubius Therapeutics, Cambridge, MA, USA

Shannon Leonard

Rubius Therapeutics, Cambridge, MA, USA

Ryan Pepi

Rubius Therapeutics, Cambridge, MA, USA

Alex Nanna

Rubius Therapeutics, Cambridge, MA, USA