Synthesis of PEITC-loaded gold nanoparticles and evaluation of the hepatoprotective effect on CCl4-induced damage through Nrf2 pathway

Uyumlu Ayşe Burçin; Çağlar Yılmaz Hatice; Satılmış Basri; Erdemoğlu Sema

doi:10.1515/tjb-2022-0208

Türk Biyokimya Dergisi (Jan 2023)

Synthesis of PEITC-loaded gold nanoparticles and evaluation of the hepatoprotective effect on CCl4-induced damage through Nrf2 pathway

Uyumlu Ayşe Burçin,
Çağlar Yılmaz Hatice,
Satılmış Basri,
Erdemoğlu Sema

Affiliations

Uyumlu Ayşe Burçin: Department of Biochemistry, Faculty of Pharmacy, İnönü University, Malatya, Turkiye
Çağlar Yılmaz Hatice: Department of Chemistry, Faculty of Arts and Science, İnönü University, Malatya, Turkiye
Satılmış Basri: Hepatology Research Laboratory, Liver Transplant Institute, İnönü University, Malatya, Turkiye
Erdemoğlu Sema: Department of Chemistry, Faculty of Arts and Science, İnönü University, Malatya, Turkiye

DOI: https://doi.org/10.1515/tjb-2022-0208
Journal volume & issue: Vol. 48, no. 1
pp. 26 – 31

Abstract

Read online

The purpose of the study was to prepare an effective and new drug delivery system for enhancing the stability of Phenethyl isothiocyanate (PEITC), and its hepatoprotective effect in the carbon tetrachloride (CCl4)-induced damage in hepatocellular carcinoma G2 (HepG2) cell line via nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway.

Published in Türk Biyokimya Dergisi

ISSN: 1303-829X (Online)
Publisher: De Gruyter
Country of publisher: Germany
LCC subjects: Science: Chemistry: Organic chemistry: Biochemistry
Website: https://www.degruyter.com/journal/key/tjb/html

About the journal

Abstract

Keywords