Communications Biology (Apr 2021)
A positive charge region of Salmonella FliI is required for ATPase formation and efficient flagellar protein export
Abstract
Kinoshita, Namba and Minamino show that a cluster of positively-charged arginines in the Salmonella FliI is necessary for formation of the FliI homo-hexamer ATPase. Through loss- and gain-of-function experiments, they demonstrate that hexamer assembly is also responsible for efficient export of flagellar proteins during flagellar assembly.