American Journal of Ophthalmology Case Reports (Dec 2021)

Chronic recurrent multifocal osteomyelitis, central retinal artery occlusion and optic neuropathy: A new association

  • Michael S. Vaphiades,
  • Kevin E. Lai,
  • Lanning B. Kline,
  • Brendan Grondines,
  • Emily Riser

Journal volume & issue
Vol. 24
p. 101209

Abstract

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Purpose: To report a patient with chronic recurrent multifocal osteomyelitis (CRMO) complicated by optic neuropathy and central retinal artery occlusion (CRAO). Observations: CRMO is a noninfectious, inflammatory bone disorder. It is thought to be an autoimmune condition related to an imbalance of pro- and anti-inflammatory cytokines. Retinal vasculitis has been reported in a patient with CRMO but not CRAO or optic neuropathy. Conclusions: We expanded the list of ophthalmic involvement of CRMO to include CRAO and optic neuropathy.

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