BMC Research Notes (Jul 2019)

Retrospective investigation of IgM antibodies against Zika virus in serum from febrile patients in Mozambique, 2009–2015

  • Imelda Rogério Chelene,
  • Sadia Ali,
  • Flora Inalda Mula,
  • Argentina Felisbela Muianga,
  • Vanessa Onofre Monteiro,
  • John Oludele,
  • Inocêncio Salvador Chongo,
  • Américo José,
  • Nádia Alves Amade,
  • Virgílio Santo António,
  • Eduardo Samo Gudo

DOI
https://doi.org/10.1186/s13104-019-4511-x
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 5

Abstract

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Abstract Objective Zika virus (ZIKV) has emerged as an important health problem worldwide. The aim of this study was to investigate the occurrence, geographical distribution and trend of immunoglobulin M (IgM) antibodies against ZIKV between 2009 and 2015 in Mozambique. Results The median age of participants was 3 years [interquartile range (IQR): 1.0–6.0 years)] and 56.5% (480/850) of them were male. Of the 850 samples, 42 (4.9%) were positive for IgM antibodies against ZIKV. Positive samples were found in 9 provinces of the country. Frequency of IgM antibodies against ZIKV was slightly higher in patients aged 5–9 years old, and in the north region of the country.

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