Glucose-6-Phosphate Acts as an Extracellular Signal of SagS To Modulate <i>Pseudomonas aeruginosa</i> c-di-GMP Levels, Attachment, and Biofilm Formation

Abstract

Pathogens sense and respond to signals and cues present in their environment, including host-derived small molecules to modulate the expression of their virulence repertoire. Here, we demonstrate that the opportunistic pathogen Pseudomonas aeruginosa