Orthogonal programming of heterogeneous micro-mechano-environments and geometries in three-dimensional bio-stereolithography

Hang Yin; Yonghui Ding; Yao Zhai; Wei Tan; Xiaobo Yin

doi:10.1038/s41467-018-06685-1

Nature Communications (Oct 2018)

Orthogonal programming of heterogeneous micro-mechano-environments and geometries in three-dimensional bio-stereolithography

Hang Yin,
Yonghui Ding,
Yao Zhai,
Wei Tan,
Xiaobo Yin

Affiliations

Hang Yin: Department of Mechanical Engineering, University of Colorado
Yonghui Ding: Department of Mechanical Engineering, University of Colorado
Yao Zhai: Department of Mechanical Engineering, University of Colorado
Wei Tan: Department of Mechanical Engineering, University of Colorado
Xiaobo Yin: Department of Mechanical Engineering, University of Colorado

DOI: https://doi.org/10.1038/s41467-018-06685-1
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 7

Abstract

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Tuning the mechanical properties of extracellular matrix is of great interest in tissue engineering but spatial control over stiffness in hydrogels has been demonstrated in two dimensions only. Here the authors developed a layer-by-layer printing technique which uses oxygen inhibition to control the heterogeneous stiffness in 3D printed structures.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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