Peripheral retinal avascularity and capillary leakage in central serous chorioretinopathy

Abstract

Purpose: To report a novel finding of peripheral retinal avascularity (PRA) and peripheral capillary leakage (PCL) on wide-field fluorescein angiography (WFA) in non-dependent quadrants, in eyes with bilateral chronic central serous chorioretinopathy (CSCR). Methods: Forty six patients with bilateral CSCR were studied. Four patients had PRA and PCL, and 42 patients did not. The demographic profile, clinical findings, and imaging characteristics of the two groups were compared. Results: There was no significant difference between those patients with and without PRA and PCL with respect to the demographic profile, clinical findings, and imaging characteristics. Laser photocoagulation to extrafoveal points of leakage seen on fluorescein angiography (FA) was sufficient to cause complete resolution of CSCR in these 4 patients. PRA areas were not treated. Conclusion: The PRA and PCL in CSCR are novel findings, which have not been previously described. Keywords: Central serous chorioretinopathy, Peripheral retinal avascularity, Peripheral capillary leakage, Wide field fluorescein angiography, Intraocular inflammation