Proteomic and transcriptomic profiles of human urothelial cancer cells with histone deacetylase 5 overexpression

Ananda Ayyappan Jaguva Vasudevan; Michèle J. Hoffmann; Gereon Poschmann; Patrick Petzsch; Constanze Wiek; Kai Stühler; Karl Köhrer; Wolfgang A. Schulz; Günter Niegisch

doi:10.1038/s41597-022-01319-0

Scientific Data (May 2022)

Proteomic and transcriptomic profiles of human urothelial cancer cells with histone deacetylase 5 overexpression

Ananda Ayyappan Jaguva Vasudevan,
Michèle J. Hoffmann,
Gereon Poschmann,
Patrick Petzsch,
Constanze Wiek,
Kai Stühler,
Karl Köhrer,
Wolfgang A. Schulz,
Günter Niegisch

Affiliations

Ananda Ayyappan Jaguva Vasudevan: Department of Urology, University Hospital and Medical Faculty, Heinrich Heine University Düsseldorf
Michèle J. Hoffmann: Department of Urology, University Hospital and Medical Faculty, Heinrich Heine University Düsseldorf
Gereon Poschmann: Institute for Molecular Medicine, Proteome Research, University Hospital and Medical Faculty, Heinrich Heine University Düsseldorf
Patrick Petzsch: Genomics & Transcriptomics Laboratory, Biological and Medical Research Centre (BMFZ), Heinrich Heine University Düsseldorf
Constanze Wiek: Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital and Medical Faculty, Heinrich Heine University Düsseldorf
Kai Stühler: Institute for Molecular Medicine, Proteome Research, University Hospital and Medical Faculty, Heinrich Heine University Düsseldorf
Karl Köhrer: Genomics & Transcriptomics Laboratory, Biological and Medical Research Centre (BMFZ), Heinrich Heine University Düsseldorf
Wolfgang A. Schulz: Department of Urology, University Hospital and Medical Faculty, Heinrich Heine University Düsseldorf
Günter Niegisch: Department of Urology, University Hospital and Medical Faculty, Heinrich Heine University Düsseldorf

DOI: https://doi.org/10.1038/s41597-022-01319-0
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 7

Abstract

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Measurement(s) RNA-seq assay • Proteome Technology Type(s) Whole Transcriptome Sequencing • Mass spectrometry intensity based label-free quantification method Factor Type(s) Effect of HDAC5 overexpression in a range of urothelial cancer cells Sample Characteristic - Organism Homo sapiens

Published in Scientific Data

ISSN: 2052-4463 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/sdata/

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