Journal of Family Medicine and Primary Care (Jan 2019)
The effect of endometrial thickness and endometrial blood flow on pregnancy outcome in intrauterine insemination cycles
Abstract
Objective: To investigate whether endometrial thickness and endometrial blood flow on the day of hCG administration is a predictor of intrauterine insemination (IUI) success. Method: A cross-sectional prospective clinical study with simple randomized sampling; Patient: 100 women experiencing the IUI cycle; Interventions: a comparison was made between pregnant and non-pregnant patients in terms of the endometrial thickness and pattern as well as the color Doppler flow on the day of hCG administration and also cycle parameters. Main outcome measures: endometrial thickness and patterns as well as the blood flow in color Doppler. Results: With the overall pregnancy rate being 38%, it was demonstrated that the endometrial blood flow was significantly greater in the cycle pregnancy obtained on the day of hCG administration, yet it was realized that the endometrial thickness and pattern of sonography did not have any predictive values for endometrial receptivity . In a multivariate analysis, the pregnancy rate was affected by the following variables: the duration of infertility, the women's age, the type number of IUI cycles, the number of injections to stimulate dominant follicles, and the sperm count. In the current study, the variability was realized to be of no predictive values for the IUI outcome, yet the endometrial flow in color Doppler was found to be positively connected with the pregnancy outcome.
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