Nature Communications (Mar 2021)
Immunogenicity and protective efficacy of inactivated SARS-CoV-2 vaccine candidate, BBV152 in rhesus macaques
- Pragya D. Yadav,
- Raches Ella,
- Sanjay Kumar,
- Dilip R. Patil,
- Sreelekshmy Mohandas,
- Anita M. Shete,
- Krishna M. Vadrevu,
- Gaurav Bhati,
- Gajanan Sapkal,
- Himanshu Kaushal,
- Savita Patil,
- Rajlaxmi Jain,
- Gururaj Deshpande,
- Nivedita Gupta,
- Kshitij Agarwal,
- Mangesh Gokhale,
- Basavaraj Mathapati,
- Siddhanath Metkari,
- Chandrashekhar Mote,
- Dimpal Nyayanit,
- Deepak Y. Patil,
- B. S. Sai Prasad,
- Annasaheb Suryawanshi,
- Manoj Kadam,
- Abhimanyu Kumar,
- Sachin Daigude,
- Sanjay Gopale,
- Triparna Majumdar,
- Deepak Mali,
- Prasad Sarkale,
- Shreekant Baradkar,
- Pranita Gawande,
- Yash Joshi,
- Sidharam Fulari,
- Hitesh Dighe,
- Sharda Sharma,
- Rashmi Gunjikar,
- Abhinendra Kumar,
- Kaumudi Kalele,
- Vellimedu K. Srinivas,
- Raman R. Gangakhedkar,
- Krishna M. Ella,
- Priya Abraham,
- Samiran Panda,
- Balram Bhargava
Affiliations
- Pragya D. Yadav
- Indian Council of Medical Research-National Institute of Virology
- Raches Ella
- Bharat Biotech International Limited, Genome Valley
- Sanjay Kumar
- Department of Neurosurgery, Command Hospital (Southern Command), Armed Forces Medical College (AFMC)
- Dilip R. Patil
- Indian Council of Medical Research-National Institute of Virology
- Sreelekshmy Mohandas
- Indian Council of Medical Research-National Institute of Virology
- Anita M. Shete
- Indian Council of Medical Research-National Institute of Virology
- Krishna M. Vadrevu
- Bharat Biotech International Limited, Genome Valley
- Gaurav Bhati
- Army Institute of Cardio-Thoracic Sciences
- Gajanan Sapkal
- Indian Council of Medical Research-National Institute of Virology
- Himanshu Kaushal
- Indian Council of Medical Research-National Institute of Virology
- Savita Patil
- Indian Council of Medical Research-National Institute of Virology
- Rajlaxmi Jain
- Indian Council of Medical Research-National Institute of Virology
- Gururaj Deshpande
- Indian Council of Medical Research-National Institute of Virology
- Nivedita Gupta
- Indian Council of Medical Research, V. Ramalingaswami Bhawan
- Kshitij Agarwal
- Indian Council of Medical Research, V. Ramalingaswami Bhawan
- Mangesh Gokhale
- Indian Council of Medical Research-National Institute of Virology
- Basavaraj Mathapati
- Indian Council of Medical Research-National Institute of Virology
- Siddhanath Metkari
- ICMR-National Institute for Research in Reproductive Health
- Chandrashekhar Mote
- Department of Veterinary Pathology, Krantisinh Nana Patil College of Veterinary Science
- Dimpal Nyayanit
- Indian Council of Medical Research-National Institute of Virology
- Deepak Y. Patil
- Indian Council of Medical Research-National Institute of Virology
- B. S. Sai Prasad
- Bharat Biotech International Limited, Genome Valley
- Annasaheb Suryawanshi
- Indian Council of Medical Research-National Institute of Virology
- Manoj Kadam
- Indian Council of Medical Research-National Institute of Virology
- Abhimanyu Kumar
- Indian Council of Medical Research-National Institute of Virology
- Sachin Daigude
- Indian Council of Medical Research-National Institute of Virology
- Sanjay Gopale
- Indian Council of Medical Research-National Institute of Virology
- Triparna Majumdar
- Indian Council of Medical Research-National Institute of Virology
- Deepak Mali
- Indian Council of Medical Research-National Institute of Virology
- Prasad Sarkale
- Indian Council of Medical Research-National Institute of Virology
- Shreekant Baradkar
- Indian Council of Medical Research-National Institute of Virology
- Pranita Gawande
- Indian Council of Medical Research-National Institute of Virology
- Yash Joshi
- Indian Council of Medical Research-National Institute of Virology
- Sidharam Fulari
- Indian Council of Medical Research-National Institute of Virology
- Hitesh Dighe
- Indian Council of Medical Research-National Institute of Virology
- Sharda Sharma
- Indian Council of Medical Research-National Institute of Virology
- Rashmi Gunjikar
- Indian Council of Medical Research-National Institute of Virology
- Abhinendra Kumar
- Indian Council of Medical Research-National Institute of Virology
- Kaumudi Kalele
- Indian Council of Medical Research-National Institute of Virology
- Vellimedu K. Srinivas
- Bharat Biotech International Limited, Genome Valley
- Raman R. Gangakhedkar
- Indian Council of Medical Research, V. Ramalingaswami Bhawan
- Krishna M. Ella
- Bharat Biotech International Limited, Genome Valley
- Priya Abraham
- Indian Council of Medical Research-National Institute of Virology
- Samiran Panda
- Indian Council of Medical Research, V. Ramalingaswami Bhawan
- Balram Bhargava
- Indian Council of Medical Research, V. Ramalingaswami Bhawan
- DOI
- https://doi.org/10.1038/s41467-021-21639-w
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 11
Abstract
SARS-CoV-2 vaccines are needed to fight the pandemic. Here, authors show protective efficacy and immunogenicity of the inactivated SARS-CoV-2 vaccine BBV152 in rhesus macaques. This vaccine is currently in clinical development.