Synthesis of Benzothiophene-Fused Pyran Derivatives via Piperidine Promoted Domino Reaction

Abstract

A new domino reaction between thioaurones and malononitrile has been reported. This reaction allows efficient access to benzothiophene-fused pyran derivatives in good yields under mild reaction conditions. The substrate scope is broad; a series of benzothiophene-fused pyran derivatives have been synthesized.