Posterior reversible encephalopathy syndrome and Wernicke encephalopathy in patient with acute graft-versus-host disease

Francesca Di Giuliano, MD; Eliseo Picchi, MD; Jacopo Scaggiante, MD; Paolo Ferrante, MD; Teresa Misciasci, MD; Valerio Da Ros, MD, PhD; Chiara Adriana Pistolese, MD; Roberto Floris, MD, PhD; Francesco Garaci, MD, PhD

Radiology Case Reports (Aug 2019)

Posterior reversible encephalopathy syndrome and Wernicke encephalopathy in patient with acute graft-versus-host disease

Francesca Di Giuliano, MD,
Eliseo Picchi, MD,
Jacopo Scaggiante, MD,
Paolo Ferrante, MD,
Teresa Misciasci, MD,
Valerio Da Ros, MD, PhD,
Chiara Adriana Pistolese, MD,
Roberto Floris, MD, PhD,
Francesco Garaci, MD, PhD

Affiliations

Francesca Di Giuliano, MD: Diagnostic Imaging Unit, Policlinico Tor Vergata, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
Eliseo Picchi, MD: Diagnostic Imaging Unit, Policlinico Tor Vergata, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy; Corresponding Author.
Jacopo Scaggiante, MD: Diagnostic Imaging Unit, Policlinico Tor Vergata, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
Paolo Ferrante, MD: Diagnostic Imaging Unit, Policlinico Tor Vergata, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
Teresa Misciasci, MD: Diagnostic Imaging Unit, Policlinico Tor Vergata, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
Valerio Da Ros, MD, PhD: Diagnostic Imaging Unit, Policlinico Tor Vergata, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
Chiara Adriana Pistolese, MD: Diagnostic Imaging Unit, Policlinico Tor Vergata, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
Roberto Floris, MD, PhD: Diagnostic Imaging Unit, Policlinico Tor Vergata, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
Francesco Garaci, MD, PhD: Neuroradiology Unit, Policlinico Tor Vergata, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy

Journal volume & issue: Vol. 14, no. 8
pp. 971 – 976

Abstract

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Graft-versus-host disease (GVHD) is an immune triggered process leading to severe immune dysregulation and organ dysfunction until death and it is one of the worst medical complications after a transplant. Patients with GVHD may have several neurological alterations: during this acute severe phase there is coexistence of various and nonspecific neurological symptoms. We are reporting a case of a 53 year old woman with severe GVHD after bone marrow transplant with acute neurological signs and symptoms. MRI study showed findings consistent with Posterior reversible encephalopathy syndrome and Wernicke encephalopathy. Keywords: Acute graft-versus-host disease, Posterior reversible encephalopathy syndrome, Wernicke encephalopathy, Magnetic resonance imaging

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: http://www.journals.elsevier.com/radiology-case-reports/

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