Nature Communications (Apr 2022)

Microridge-like structures anchor motile cilia

  • Takayuki Yasunaga,
  • Johannes Wiegel,
  • Max D. Bergen,
  • Martin Helmstädter,
  • Daniel Epting,
  • Andrea Paolini,
  • Özgün Çiçek,
  • Gerald Radziwill,
  • Christina Engel,
  • Thomas Brox,
  • Olaf Ronneberger,
  • Peter Walentek,
  • Maximilian H. Ulbrich,
  • Gerd Walz

DOI
https://doi.org/10.1038/s41467-022-29741-3
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 14

Abstract

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Motile cilia beat in a defined direction to orchestrate developmental programs, but also to execute janitorial tasks such as clearing airways. Here they show that motile cilia of the Xenopus epidermis are anchored to microridge-like membrane protrusions to maintain their directionality.