Antiviral Effects of Green Tea EGCG and Its Potential Application against COVID-19

Ying-Qi Wang; Qing-Sheng Li; Xin-Qiang Zheng; Jian-Liang Lu; Yue-Rong Liang

doi:10.3390/molecules26133962

Molecules (Jun 2021)

Antiviral Effects of Green Tea EGCG and Its Potential Application against COVID-19

Ying-Qi Wang,
Qing-Sheng Li,
Xin-Qiang Zheng,
Jian-Liang Lu,
Yue-Rong Liang

Affiliations

Ying-Qi Wang: Tea Research Institute, Zhejiang University, Hangzhou 310058, China
Qing-Sheng Li: Institute of Sericulture and Tea, Zhejiang Academy of Agricultural Sciences, Hangzhou 310000, China
Xin-Qiang Zheng: Tea Research Institute, Zhejiang University, Hangzhou 310058, China
Jian-Liang Lu: Tea Research Institute, Zhejiang University, Hangzhou 310058, China
Yue-Rong Liang: Tea Research Institute, Zhejiang University, Hangzhou 310058, China

DOI: https://doi.org/10.3390/molecules26133962
Journal volume & issue: Vol. 26, no. 13
p. 3962

Abstract

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(–)-Epigallocatechin-3-O-gallate (EGCG), the most abundant component of catechins in tea (Camellia sinensis (L.) O. Kuntze), plays a role against viruses through inhibiting virus invasiveness, restraining gene expression and replication. In this paper, the antiviral effects of EGCG on various viruses, including DNA virus, RNA virus, coronavirus, enterovirus and arbovirus, were reviewed. Meanwhile, the antiviral effects of the EGCG epi-isomer counterpart (+)-gallocatechin-3-O-gallate (GCG) were also discussed.

Published in Molecules

ISSN: 1420-3049 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Chemistry: Organic chemistry
Website: http://www.mdpi.com/journal/molecules

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