Genetic variation in cis-regulatory domains suggests cell type-specific regulatory mechanisms in immunity

Diana Avalos; Guillaume Rey; Diogo M. Ribeiro; Anna Ramisch; Emmanouil T. Dermitzakis; Olivier Delaneau

doi:10.1038/s42003-023-04688-3

Communications Biology (Mar 2023)

Genetic variation in cis-regulatory domains suggests cell type-specific regulatory mechanisms in immunity

Diana Avalos,
Guillaume Rey,
Diogo M. Ribeiro,
Anna Ramisch,
Emmanouil T. Dermitzakis,
Olivier Delaneau

Affiliations

Diana Avalos: Department of Genetic Medicine and Development, University of Geneva
Guillaume Rey: Department of Genetic Medicine and Development, University of Geneva
Diogo M. Ribeiro: Swiss Institute of Bioinformatics (SIB), University of Geneva
Anna Ramisch: Department of Genetic Medicine and Development, University of Geneva
Emmanouil T. Dermitzakis: Department of Genetic Medicine and Development, University of Geneva
Olivier Delaneau: Swiss Institute of Bioinformatics (SIB), University of Geneva

DOI: https://doi.org/10.1038/s42003-023-04688-3
Journal volume & issue: Vol. 6, no. 1
pp. 1 – 11

Abstract

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An analysis of cis-regulatory domains (CRDs) among monocytes, neutrophils, and T cells derived from ChIP-seq peaks and methylation data suggests cell-type specific regulatory mechanisms of immunity.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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