Nature Communications (Mar 2022)
Isolation of infectious Lloviu virus from Schreiber’s bats in Hungary
- Gábor Kemenesi,
- Gábor E. Tóth,
- Martin Mayora-Neto,
- Simon Scott,
- Nigel Temperton,
- Edward Wright,
- Elke Mühlberger,
- Adam J. Hume,
- Ellen L. Suder,
- Brigitta Zana,
- Sándor A. Boldogh,
- Tamás Görföl,
- Péter Estók,
- Zsófia Lanszki,
- Balázs A. Somogyi,
- Ágnes Nagy,
- Csaba I. Pereszlényi,
- Gábor Dudás,
- Fanni Földes,
- Kornélia Kurucz,
- Mónika Madai,
- Safia Zeghbib,
- Piet Maes,
- Bert Vanmechelen,
- Ferenc Jakab
Affiliations
- Gábor Kemenesi
- National Laboratory of Virology, Szentágothai Research Centre, University of Pécs
- Gábor E. Tóth
- National Laboratory of Virology, Szentágothai Research Centre, University of Pécs
- Martin Mayora-Neto
- Viral Pseudotype Unit, Medway School of Pharmacy, Chatham Maritime, Universities of Kent & Greenwich
- Simon Scott
- Viral Pseudotype Unit, Medway School of Pharmacy, Chatham Maritime, Universities of Kent & Greenwich
- Nigel Temperton
- Viral Pseudotype Unit, Medway School of Pharmacy, Chatham Maritime, Universities of Kent & Greenwich
- Edward Wright
- Viral Pseudotype Unit, School of Life Sciences, University of Sussex, Falmer
- Elke Mühlberger
- Department of Microbiology, Boston University School of Medicine
- Adam J. Hume
- Department of Microbiology, Boston University School of Medicine
- Ellen L. Suder
- Department of Microbiology, Boston University School of Medicine
- Brigitta Zana
- National Laboratory of Virology, Szentágothai Research Centre, University of Pécs
- Sándor A. Boldogh
- Aggtelek National Park Directorate
- Tamás Görföl
- National Laboratory of Virology, Szentágothai Research Centre, University of Pécs
- Péter Estók
- Department of Zoology, Eszterházy Károly University
- Zsófia Lanszki
- National Laboratory of Virology, Szentágothai Research Centre, University of Pécs
- Balázs A. Somogyi
- National Laboratory of Virology, Szentágothai Research Centre, University of Pécs
- Ágnes Nagy
- Medical Centre, Hungarian Defence Forces
- Csaba I. Pereszlényi
- Medical Centre, Hungarian Defence Forces
- Gábor Dudás
- Medical Centre, Hungarian Defence Forces
- Fanni Földes
- National Laboratory of Virology, Szentágothai Research Centre, University of Pécs
- Kornélia Kurucz
- National Laboratory of Virology, Szentágothai Research Centre, University of Pécs
- Mónika Madai
- National Laboratory of Virology, Szentágothai Research Centre, University of Pécs
- Safia Zeghbib
- National Laboratory of Virology, Szentágothai Research Centre, University of Pécs
- Piet Maes
- Leuven, Rega Institute, Department of Microbiology, Immunology and Transplantation, Laboratory of Clinical and Epidemiological Virology
- Bert Vanmechelen
- Leuven, Rega Institute, Department of Microbiology, Immunology and Transplantation, Laboratory of Clinical and Epidemiological Virology
- Ferenc Jakab
- National Laboratory of Virology, Szentágothai Research Centre, University of Pécs
- DOI
- https://doi.org/10.1038/s41467-022-29298-1
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 11
Abstract
Lloviu virus (LLOV) is a filovirus that was first identified in 2002 in Schreiber’s bats in Europe. Here, the authors isolate infectious LLOV from Schreiber’s bats in Hungary and show that it can infect human cells in vitro, suggesting potential for zoonotic events. They furthermore detect LLOV RNA in ectoparasites of sampled bats.