Repositioning of Dantrolene as a Multitarget Agent for Neurodegenerative Diseases

Isabella Bolognino; Marco Catto; Leonardo Pisani; Saverio Cellamare; Cosimo D. Altomare; Nicola Giangregorio

doi:10.3390/proceedings2019022007

Proceedings (Aug 2019)

Repositioning of Dantrolene as a Multitarget Agent for Neurodegenerative Diseases

Isabella Bolognino,
Marco Catto,
Leonardo Pisani,
Saverio Cellamare,
Cosimo D. Altomare,
Nicola Giangregorio

Affiliations

Isabella Bolognino: Department of Pharmacy-Drug Sciences, University of Bari “Aldo Moro”, via E. Orabona 4, 70125 Bari, Italy
Marco Catto: Department of Pharmacy-Drug Sciences, University of Bari “Aldo Moro”, via E. Orabona 4, 70125 Bari, Italy
Leonardo Pisani: Department of Pharmacy-Drug Sciences, University of Bari “Aldo Moro”, via E. Orabona 4, 70125 Bari, Italy
Saverio Cellamare: Department of Pharmacy-Drug Sciences, University of Bari “Aldo Moro”, via E. Orabona 4, 70125 Bari, Italy
Cosimo D. Altomare: Department of Pharmacy-Drug Sciences, University of Bari “Aldo Moro”, via E. Orabona 4, 70125 Bari, Italy
Nicola Giangregorio: National Research Council, Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies (CNR-IBIOM), via G. Amendola 122/O, 70126 Bari, Italy

DOI: https://doi.org/10.3390/proceedings2019022007
Journal volume & issue: Vol. 22, no. 1
p. 7

Abstract

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Dantrolene is an orphan drug representing the sole therapeutic treatment for malignant hyperthermia, a life-threatening pathology affecting 0.2 in every 10,000 people in the EU. [...]

Published in Proceedings

ISSN: 2504-3900 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: General Works
Website: http://www.mdpi.com/journal/proceedings

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