Preeclampsia (PE) is a complex illness of the human gestation

Abstract

Preeclampsia (PE) is a complex illness of the human gestation. It is responsible for a high perinatal morbimortality.It is the illness of the multiple theories; in one environmentaland genetic factors are associated to explain it. To find genes candidates to be associated with PE, two methodology types are used: association and binding studies. In this paper we presented the foundation of both studies that explain the main genes candidates to involve in the genesis of this illness,like that ones that code for the methylenetetrahydrofolatereductase, lipoprotein lipase and endothelial nitric oxidesintase, Leiden‘s V factor, angiotensinogen, HLA-G, alphatumoral necrosis factor.

Keywords

• Genetics
• preeclampsia
• polimorphisms
• association studies
• binding studies
• methylenetetrahydrofolatereductase
• lipoprotein lipase
• endothelial nitric oxide sintase
• Leiden‘s V factor
• angiotensinogen
• HLA-G alpha tumoral necrosis factor.