PP 1.24 – 00132 BET PROTACS Reveal BRD4 Disruption of the 7SK/P-TEFb Equilibrium is Critical for Effective Reactivation of Latent HIV in CD4+ T-cells

• A-M. Turner,
• F. Potjewyd,
• S. Falcinelli,
• J. Fox,
• J. Kirchherr,
• B. Allard,
• N. Archin,
• L. James,
• D. Margolis

Affiliations

A-M. Turner

UNC HIV Cure Center, Department of Medicine, Infectious Diseases, Chapel Hill, USA

F. Potjewyd

Center For Integrative Chemical Biology And Drug Discovery, Eshelman School of Pharmacy, Chapel Hill, USA

S. Falcinelli

UNC HIV Cure Center, Chapel Hill, USA

J. Fox

UNC HIV Cure Center, Chapel Hill, USA

J. Kirchherr

UNC HIV Cure Center, Chapel Hill, USA

B. Allard

UNC HIV Cure Center, Chapel Hill, USA

N. Archin

UNC HIV Cure Center, Department of Medicine, Infectious Diseases, Chapel Hill, USA

L. James

Center For Integrative Chemical Biology And Drug Discovery, Eshelman School of Pharmacy, Chapel Hill, USA

D. Margolis

UNC HIV Cure Center, Department of Medicine, Infectious Diseases, Chapel Hill, USA