npj Primary Care Respiratory Medicine (Jan 2022)
The 1-minute sit-to-stand test to detect desaturation during 6-minute walk test in interstitial lung disease
- Keiji Oishi,
- Kazuto Matsunaga,
- Maki Asami-Noyama,
- Tasuku Yamamoto,
- Yukari Hisamoto,
- Tetsuya Fujii,
- Misa Harada,
- Junki Suizu,
- Keita Murakawa,
- Ayumi Chikumoto,
- Kazuki Matsuda,
- Haruka Kanesada,
- Yujiro Kikuchi,
- Kazuki Hamada,
- Sho Uehara,
- Ryo Suetake,
- Syuichiro Ohata,
- Yoriyuki Murata,
- Yoshikazu Yamaji,
- Kenji Sakamoto,
- Kosuke Ito,
- Hisayuki Osoreda,
- Nobutaka Edakuni,
- Tomoyuki Kakugawa,
- Tsunahiko Hirano,
- Masafumi Yano
Affiliations
- Keiji Oishi
- Department of Medicine and Clinical Science, Graduate School of Medicine, Yamaguchi University
- Kazuto Matsunaga
- Department of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University
- Maki Asami-Noyama
- Department of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University
- Tasuku Yamamoto
- Department of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University
- Yukari Hisamoto
- Department of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University
- Tetsuya Fujii
- Department of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University
- Misa Harada
- Department of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University
- Junki Suizu
- Department of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University
- Keita Murakawa
- Department of Respiratory Medicine, National Hospital Organization Yamaguchi-Ube Medical Center
- Ayumi Chikumoto
- Department of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University
- Kazuki Matsuda
- Department of Respiratory Medicine, National Hospital Organization Yamaguchi-Ube Medical Center
- Haruka Kanesada
- Department of Respiratory Medicine, National Hospital Organization Yamaguchi-Ube Medical Center
- Yujiro Kikuchi
- Department of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University
- Kazuki Hamada
- Department of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University
- Sho Uehara
- Department of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University
- Ryo Suetake
- Department of Respiratory Medicine, National Hospital Organization Yamaguchi-Ube Medical Center
- Syuichiro Ohata
- Department of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University
- Yoriyuki Murata
- Department of Medicine and Clinical Science, Graduate School of Medicine, Yamaguchi University
- Yoshikazu Yamaji
- Department of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University
- Kenji Sakamoto
- Department of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University
- Kosuke Ito
- Department of Respiratory Medicine, National Hospital Organization Yamaguchi-Ube Medical Center
- Hisayuki Osoreda
- Department of Respiratory Medicine, National Hospital Organization Yamaguchi-Ube Medical Center
- Nobutaka Edakuni
- Department of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University
- Tomoyuki Kakugawa
- Department of Pulmonology and Gerontology, Graduate School of Medicine, Yamaguchi University
- Tsunahiko Hirano
- Department of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University
- Masafumi Yano
- Department of Medicine and Clinical Science, Graduate School of Medicine, Yamaguchi University
- DOI
- https://doi.org/10.1038/s41533-022-00268-w
- Journal volume & issue
-
Vol. 32,
no. 1
pp. 1 – 6
Abstract
Abstract Although the 6 min walk test (6MWT) is well-established for assessing desaturation in patients with interstitial lung disease (ILD), it cannot be easily performed in primary healthcare settings. This retrospective observational study aimed to evaluate the usefulness of the 1 min sit-to-stand test (1STST) for assessing desaturation during 6MWT in ILD patients with normal resting blood oxygen levels. We included 116 patients, and the pulse oxygen saturation (SpO2) for both methods was analyzed. The SpO2 nadir during the 1STST and 6MWT correlated strongly (ρ = 0.82). The frequency of patients with nadir SpO2 < 90% was consistent for both tests (κ = 0.82). 1STST was superior to diffusing capacity for carbon monoxide in detecting desaturation during the 6MWT. These findings were similarly stratified according to performance status or dyspnea scale. The 1STST can easily measure exertional desaturation in ILD patients with normal resting blood oxygen levels and is an alternative to the 6MWT.
