The Effect of Diabetes Mellitus on Non-Motor Symptoms in Parkinson’s Diseas

Abstract

Aim: The aim of the study is to investigate the effect of diabetes mellitus (DM) on non-motor symptoms in Parkison’s Disease (PD). Patients and Methods: The study included 73 patients with DM and 30 without DM who were followed-up with the diagnosis of PD at the neurology outpatient clinic. The United Parkinson's Disease Rating Scale (UPDRS) and Hoehn Yahr Staging (HYE) was performed. In both groups Non-motor Symptoms Questionnaire (NMSQ), Beck Depression Inventory (BDI), Hamilton Anxiety Inventory (HAI), Pitsburg Sleep Quality Scale (PSQI), Epworth Sleepiness Scale (ESS) and Insomnia Severity Index (ISI) were performed. Results: There was no significant difference between the two groups in terms of HAI, BDI, ISI and ESS scores. There was no significant difference in the rates of depression, anxiety disorders and daytime sleepiness in the groups with and without DM. According to the PSQI, the ratio of those with poor sleep was the same. When all the questions of the non-motor symptoms questionnaire were evaluated separately, the ratio of those who answered yes to the question ‘’Was there excessive sweating?’’ was significantly higher in the diabetic group (p = 0.036). The risk of excessive sweating in patients with PD who had DM was 13 times higher than those without DM. Coclusion: DM is a parameter that increases the rate of excessive sweating in patients with PD.

Keywords

• parkinson hastalığı
• diyabet
• non-motor semptomlar
• parkinson's disease
• diabetes mellitus
• non-motor symptoms