172 Overcoming immunosuppressive TGF-β signaling in human ovarian cancer-derived tumor infiltrating lymphocytes via non-viral CRISPR engineering

• Sanjay Kumar,
• Patrick Hwu,
• Chantale Bernatchez,
• Amir Jazaeri,
• Marie-Andree Forget,
• Donastas Sakellariou-Thompson,
• Rafet Basar,
• Yunfei Wang,
• Samantha Fix,
• Ana Lucía Dominguez,
• Christopher Reyes,
• Larissa Meyer

Affiliations

Sanjay Kumar

2 Urology, SMS Medical College & Attached Hospitals, Jaipur, Rajasthan, India

Patrick Hwu

Department of Melanoma, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Chantale Bernatchez

Department of Melanoma, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Amir Jazaeri

1 Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Marie-Andree Forget

Department of Melanoma, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Donastas Sakellariou-Thompson

Aff1 grid.240145.60000000122914776The Department of Melanoma Medical OncologyThe University of Texas MD Anderson Cancer Center Houston TX USA

Rafet Basar

1The University of Texas MDACC, Houston, USA

Yunfei Wang

Department of Psychiatry, The Second Xiangya Hospital, Central South University, Changsha, China

Samantha Fix

1MD Anderson Cancer Center, Houston, TX, USA

Ana Lucía Dominguez

1MD Anderson Cancer Center, Houston, TX, USA

Christopher Reyes

2Thermo Fisher Scientific, Carlsbad, CA, USA

Larissa Meyer

1MD Anderson Cancer Center, Houston, TX, USA