The Role of Exosomes in Viral Hepatitis and Its Associated Liver Diseases

Hao Zhou; Zhi-han Yan; Yuan Yuan; Chen Xing; Nan Jiang

doi:10.3389/fmed.2021.782485

Frontiers in Medicine (Nov 2021)

The Role of Exosomes in Viral Hepatitis and Its Associated Liver Diseases

Hao Zhou,
Zhi-han Yan,
Yuan Yuan,
Chen Xing,
Nan Jiang

Affiliations

Hao Zhou: Affiliated Hangzhou Chest Hospital, Zhejiang University School of Medicine, Hangzhou, China
Zhi-han Yan: Department of Hepatology, Wuxi Fifth People's Hospital, Wuxi, China
Yuan Yuan: Affiliated Hangzhou Chest Hospital, Zhejiang University School of Medicine, Hangzhou, China
Chen Xing: Department of Oncology, The Second People's Hospital of Yancheng City, Yancheng, China
Nan Jiang: Department of Urology, People's Hospital of Dongtai City, Dongtai, China

DOI: https://doi.org/10.3389/fmed.2021.782485
Journal volume & issue: Vol. 8

Abstract

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Exosomes, the important carriers between cells, can carry proteins, micro ribonucleic acids (miRNAs), long non-coding RNAs (lncRNAs) and other molecules to mediate cellular information transduction. They also play an important role in the pathogenesis, prognosis and treatment of viral hepatitis and its associated liver diseases. Several studies have reported that viral hepatitis and its associated liver diseases, including hepatitis A, B, C and E; hepatic fibrosis and hepatocellular carcinoma, were closely associated with exosomes. Exploring the role of exosomes in viral hepatitis and associated liver diseases will enhance our understanding of these diseases. Therefore, this review mainly summarised the role of exosomes in viral hepatitis and its associated liver diseases to identify new strategies for liver diseases in clinical practise.

Published in Frontiers in Medicine

ISSN: 2296-858X (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Medicine (General)
Website: http://www.frontiersin.org/journals/medicine

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Abstract

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