A radiogenomics application for prognostic profiling of endometrial cancer

Erling A. Hoivik; Erlend Hodneland; Julie A. Dybvik; Kari S. Wagner-Larsen; Kristine E. Fasmer; Hege F. Berg; Mari K. Halle; Ingfrid S. Haldorsen; Camilla Krakstad

doi:10.1038/s42003-021-02894-5

Communications Biology (Dec 2021)

A radiogenomics application for prognostic profiling of endometrial cancer

Erling A. Hoivik,
Erlend Hodneland,
Julie A. Dybvik,
Kari S. Wagner-Larsen,
Kristine E. Fasmer,
Hege F. Berg,
Mari K. Halle,
Ingfrid S. Haldorsen,
Camilla Krakstad

Affiliations

Erling A. Hoivik: Centre for Cancer Biomarkers, Department of Clinical Science, University of Bergen
Erlend Hodneland: Mohn Medical Imaging and Visualization Centre (MMIV), Department of Radiology, Haukeland University Hospital
Julie A. Dybvik: Mohn Medical Imaging and Visualization Centre (MMIV), Department of Radiology, Haukeland University Hospital
Kari S. Wagner-Larsen: Mohn Medical Imaging and Visualization Centre (MMIV), Department of Radiology, Haukeland University Hospital
Kristine E. Fasmer: Mohn Medical Imaging and Visualization Centre (MMIV), Department of Radiology, Haukeland University Hospital
Hege F. Berg: Centre for Cancer Biomarkers, Department of Clinical Science, University of Bergen
Mari K. Halle: Centre for Cancer Biomarkers, Department of Clinical Science, University of Bergen
Ingfrid S. Haldorsen: Mohn Medical Imaging and Visualization Centre (MMIV), Department of Radiology, Haukeland University Hospital
Camilla Krakstad: Centre for Cancer Biomarkers, Department of Clinical Science, University of Bergen

DOI: https://doi.org/10.1038/s42003-021-02894-5
Journal volume & issue: Vol. 4, no. 1
pp. 1 – 12

Abstract

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Hoivik, Hodneland and colleagues employ convoluted neural networks alongside radiogenomic biomarkers to profile endometrial tumors. They identify an 11-gene high-risk signature validated with retrospective patient data.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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