Circ_WWC3 overexpression decelerates the progression of osteosarcoma by regulating miR-421/PDE7B axis

Liu Sihai; Zhang Jing; Zheng Ting; Mou Xiongneng; Xin Wenwei

doi:10.1515/biol-2021-0021

Open Life Sciences (Mar 2021)

Circ_WWC3 overexpression decelerates the progression of osteosarcoma by regulating miR-421/PDE7B axis

Liu Sihai,
Zhang Jing,
Zheng Ting,
Mou Xiongneng,
Xin Wenwei

Affiliations

Liu Sihai: Department of Orthopedics, Wuhan Third Hospital, Tongren Hospital of Wuhan University, Wuhan, Hubei, 430060, China
Zhang Jing: Taizhou Vocational and Technical College, Taizhou, Zhejiang, 318000, China
Zheng Ting: Department Emergency, Taizhou First People’s Hospital, No. 218 Hengjie Road, Huangyan District, Taizhou, Zhejiang, 318020, China
Mou Xiongneng: Department Emergency, Taizhou First People’s Hospital, No. 218 Hengjie Road, Huangyan District, Taizhou, Zhejiang, 318020, China
Xin Wenwei: Department Emergency, Taizhou First People’s Hospital, No. 218 Hengjie Road, Huangyan District, Taizhou, Zhejiang, 318020, China

DOI: https://doi.org/10.1515/biol-2021-0021
Journal volume & issue: Vol. 16, no. 1
pp. 229 – 241

Abstract

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Emerging evidence has shown that circular RNAs (circRNAs) are vital regulators in osteosarcoma (OS) progression. However, the effects of circ_WWC3 in OS have not been explored. In this research, the functions and mechanisms of circ_WWC3 in OS were investigated.

Published in Open Life Sciences

ISSN: 2391-5412 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Science: Biology (General)
Website: http://www.degruyter.com/view/j/biol

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