PHENOLIC COMPOUND FROM THE STEM BARK OF MANGGIS HUTAN (Garcinia bancana Miq.) AND THEIR ANTIOXIDANT ACTIVITY

Muharni Muharni; Supriyatna Supriyatna; Husein H. Bahti; Dachriyanus Dachriyanus

doi:10.22146/ijc.21550

Indonesian Journal of Chemistry (Jun 2010)

PHENOLIC COMPOUND FROM THE STEM BARK OF MANGGIS HUTAN (Garcinia bancana Miq.) AND THEIR ANTIOXIDANT ACTIVITY

Muharni Muharni,
Supriyatna Supriyatna,
Husein H. Bahti,
Dachriyanus Dachriyanus

Affiliations

Muharni Muharni: Department of Chemistry, Faculty of Mathematics and Natural Sciences, Sriwijaya University, Ogan Ilir, Sumatera Selatan
Supriyatna Supriyatna: Faculty of Pharmacy, Padjadjaran University, Jatinangor, Sumedang, Indonesia
Husein H. Bahti: Department of Chemistry, Faculty of Mathematics and Natural Sciences, Padjadjaran University, Jatinangor, Sumedang
Dachriyanus Dachriyanus: Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Andalas University, Limau Manis, Padang

DOI: https://doi.org/10.22146/ijc.21550
Journal volume & issue: Vol. 9, no. 2
pp. 321 – 327

Abstract

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A phenolic compoud, (-)-epicatechin, was isolated from the stem bark of Garcinia bancana. The structure of this compound was determined base on spectroscopic data such as including UV, IR, 1-D, 2-D NMR, and comparison with the reported data. Biological activity of this compound at free radical scavenging activity by 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) and inhibitory xanthine oxidase(XO) activity showed that (-)- epicathechin active at two methods with IC50 value 8.1 and 8.6 mg/mL respectively. Keywords: phenolic, (-)-epicatechin, Garcinia bancana, DPPH, XO

Published in Indonesian Journal of Chemistry

ISSN: 1411-9420 (Print); 2460-1578 (Online)
Publisher: Department of Chemistry, Universitas Gadjah Mada
Country of publisher: Indonesia
LCC subjects: Science: Chemistry
Website: https://jurnal.ugm.ac.id/ijc/

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