BMC Women's Health (May 2022)

Health-related quality of life and associated factors in Chinese menstrual migraine patients: a cross-sectional study

  • Wenxiu Luo,
  • Xing Cao,
  • Jiayu Zhao,
  • Jiaming Yang,
  • Yu Cen,
  • Jinlong He,
  • Jing Luo,
  • Yunling Zhong,
  • Ying Luo,
  • Xinyue Wang,
  • Liqiu Yang,
  • Xingyu Feng,
  • Xiaoqing Pang,
  • Jiazhu Zhang,
  • Jiaming Luo

DOI
https://doi.org/10.1186/s12905-022-01760-8
Journal volume & issue
Vol. 22, no. 1
pp. 1 – 7

Abstract

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Abstract Background Menstrual migraine is a particular form of migraine with a significant impact on the quality of life for women afflicted. Presently, no study has reported the quality of life in menstrual migraine patients. This work aims to assess the health-related quality of life and identify its associated factors among Chinese menstrual migraine patients. Methods The cross-sectional study group consisted of 109 patients with menstrual migraine, and the control group consisted of 397 female patients with non-menstrual migraine. In total, 506 patients completed questionnaires for demographic and clinical information, the Self-rating Idea of Suicide Scale, the Hamilton Depression Scale, the Hamilton Anxiety Scale, the Headache Impact Test-6, the Perceived Social Support Scale, the Pittsburgh Sleep Quality Index. Health-related quality of life was measured using the 36-Item Short Form Survey. Results Compared with non-menstrual migraine patients, five dimensions of health-related quality of life were all found to be significantly impaired in menstrual migraine patients. Headache frequency (ß = − 0.218, P = 0.014), the impact of headache on daily life (ß = − 0.270, P = 0.002), depression symptoms (ß = − 0.345, P < 0.001) were significantly associated with physical component summary, depression symptoms (ß = − 0.379, P < 0.001), social support (ß = 0.270, P < 0.001), suicidal ideation (ß = − 0.344, P < 0.001) were closely related to mental component summary. Conclusion Menstrual migraine patients had a significantly poorer health-related quality of life in many domains than non-menstrual migraine patients. Headache frequency, the impact of headache on daily life, depression symptoms, social support, and suicidal ideation were significantly associated with health-related quality of life in menstrual migraine patients. Trial registration: ChiCTR1800014343. This study was registered prospectively on 7 January 2018 at Chinese Clinical Trial registry. http://www.chictr.org.cn/showproj.aspx?proj=24526

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