Efficacy of domestic anthelmintic drug mitranox and therapy dose titration against moniesiosis and nematodosis in sheep

Abstract

Efficacy of mitranox, a domestic anthhelmintic drug of the group of acetylated salicylanilides, is tested. Experiments were conducted on sheep spontaneously infected with Mоniezia expansa, М. benedini, gastrointestinal nematodes and Muel- lerius capillaris. Mitranox was administered at the dose of 50, 75 and 100 mg/kg orally, individually, as a single dose in form of water suspension. Efficacy of mi- tranox at moniesiosis at the dose of 50, 75 и 100 mg/kg made respectively 73,3 %, 94,2 и 100 %. The highest efficacy of mitranox applied at the dose of 100 mg/kg against nematodes, gastrointestinal strongylatosis, trichocephalosis and mulleriosis made respectively 97,4 %, 97,2; 86,9 and 93,2 %. The dose of 100 mg/kg is rec- ommended for treatment of moniesiosis and nematodosis in sheep.

Keywords

• anthhelmintic drug
• mitranox
• moniesiosis
• nematodosis
• dose
• ef-ficacy
• toxicity
• sheep