ImmunoAnalysis (Jun 2022)
Electrochemical Sensing Platform Based on The Modified Carbon-Ceramic Electrode Using Multiwalled Carbon Nanotubes (MWCNTs) Through The Sol-Gel Process: Application in Sensitive Determination of Morin as A Common Flavonoids
Abstract
Background: Morin is one of the most common flavonoids which found in nature, plantsand vegetable-derived foods and Brazilian yellow tree is a source for its extraction.Because of hydroxyl group existence, Morin represents better antioxidant properties andhave great significance in bio electrochemistry-based investigations. Methods: In this research work, an electrochemical-based sensing platform was designedbased on a modified carbon-ceramic electrode (CCE) through a sol-gel process withcarbon nanotubes for the investigation of the electrochemical behavior of Morin. Various electrochemical techniques have been used for the analytical investigation ofthe proposed sensing platform including cyclic voltammetry (CV), differential pulsevoltammetry (DPV), and anodic stripping voltammetry (ASV) methods. Furthermore, themorphological investigation was efficiently performed for the demonstration of electrodesurface characteristics. Results: The obtained results showed that the anodic peak currents increased linearly in aconcentration range of 0.7–3 μM, where detection limit is equal to 0.27 μM for DPV, andthe linear range is considered to be 0.6-4 μM where there is a lower detection limit of 0.3μM for ASV. Such a biosensing assay can also prove a great potential for the determinationof Morin in dry tea. Conclusion: As clearly demonstrated, Morin as one of the flavonoids which is a pentahydroxy flavone that is 7-hydroxy flavonol bearing three additional hydroxy substituents atpositions 2’ 4’ and 5. There are many conventional analytical methods for determinationof Morin. However, electrochemical-based sensing assay are cheaper, simpler and moreeconomical. Therefore, in this research work, we have used electrochemical-basedtechniques applying CCE modified MWCNTs and appropriate analytical features havebeen obtained.
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