Case Reports in Medicine (Jan 2018)

Primary Signet Ring Cell Carcinoma of Rectum Diagnosed by Boring Biopsy in Combination with Endoscopic Mucosal Resection

  • Yoshito Hirata,
  • Keishi Kanno,
  • Nobusuke Kishikawa,
  • Shinji Tomoda,
  • Kazuki Kimura,
  • Tomoki Kobayashi,
  • Daisuke Miyamori,
  • Yuichiro Otani,
  • Masafumi Mizooka,
  • Koji Arihiro,
  • Shiro Oka,
  • Shinji Tanaka,
  • Susumu Tazuma

DOI
https://doi.org/10.1155/2018/5860815
Journal volume & issue
Vol. 2018

Abstract

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A 46-year-old man with severe back pain visited our hospital. Magnetic resonance imaging revealed extensive bone metastasis and rectal wall thickness. Colonoscopy revealed circumferential stenosis with edematous mucosa, suggesting colon cancer. However, histological findings of biopsy specimens revealed inflammatory cells but no malignant cells. The patient underwent endoscopic ultrasound, which demonstrated edematous wall thickness without destruction of the normal layer structure. After unsuccessful detection of neoplastic cells by boring biopsies, we performed endoscopic mucosal resection followed by boring biopsies that finally revealed signet ring cell carcinoma. Herein, we present a case and provide a review of the literature.