Assessment of diagnostic value of age for meridional amblyopia with Logistic regression and receiver operating characteristic curve

Abstract

AIM: To assess the diagnostic value of age for meridional amblyopia by Logistic regression and receiver operating characteristic(ROC)curve.METHODS: A total of 1 005 children(1 910 eyes)with unknown ocular abnormalities other than with-the-rule astigmatism(aged 4-8 years)were recruited. Astigmatism >or =1.00D and sphere RESULTS: The model 1 included 4 parameters(sex, astigmatism type, diopter of cylinder and diopter of sphere). The model 2 included 5 parameters(the 4 parameters of the model 1 adding age). Using Logistic regression, the diopter of cylinder had an influence on the diagnosis of meridional amblyopia in two models. In model 2, age was another influencing factor on the diagnosis of meridional amblyopia. The model 1 area under ROC curve(AUC)was 0.64, and the model 2 was 0.74. The area of model 2 was greater than the model 1. There was statistical difference in the AUC of two models(PCONCLUSION: Age might be an influential factor on the diagnosis of meridional amblyopia using Logistic regression and ROC curve.

Keywords

• children
• astigmatism
• meridional amblyopia
• Logistic regression
• receiver operating characteristic curve