Development of cell technologies and our experience of using them at the pathologies in experiment

Abstract

Development of modern cell biotechnologies provides fundamental basis for the solution of many problems of modern medicine. The result of experimental researches showed huge opportunities offered by using cell biotechnologies. Group of cell technologies as part of the laboratory of experimental surgery of East Siberian Scientific Center SB RAMS (ESSC SB RAMS) opened in 1996 had a purpose to develop new technologies on the basis of method of cell biotechnologies. Employees of Irkutsk Scientific Center of Surgery and Traumatology developed original cell technologies that allowed to prepare cell material for the correction of pathological process in animal experiments. Technology of preparation of isolated liver cells, isolated and cultivated spleen cells, Langerhans islets, long-term cryopreservation of prepared material allows to create reserve supplies to use them as required. Using xenogenic biomaterial has some advantages over using allogenic biomaterial - such as availability, opportunity for precise research of the donor, prevention of contamination of the recipient with different infections, absence of "law factor".

Keywords

• cell biotechnologies
• transplantation
• pathology