CLINICAL AND ECONOMIC BENEFITS OF HUMAN INSULIN ANALOGUESUSE

Abstract

to conduct analysis of basal-bolus insulin detemir/aspart in comparison with the NPH/human insulin for the treatment of patients with diabetes mellitus type 1 in Russia. We evaluate results of PREDICTIVE study using pharmacoeconomic analyses: «cost – effectiveness,» «cost – utility» and « budget impact». Analysis included the most widely known insulins: Protaphane®, Actrapid®, NovoRapid® and Levemir® . The period of analysis was 1 year. Additional costs for insulin transition (Protaphane® /Actrapid® to Levemir® /NovoRapid®) were 21774 rubles per patient/year, while the cost of an averted severe hypoglycemia was 24728 rubles. The reduced frequency of severe hypoglycemia (Levemir® /NovoRapid®) con

Keywords

• diabetes mellitus
• insulin detemir
• insulin aspart