Outcomes and factors influencing outcomes of critically ill HIV-positive patients in a tertiary care center in South India

Abstract

The incidence of (Human immune deficiency) HIV in India has fallen by 58% since the onset of the HIV epidemic. As of 2016 there are 2.1 million people living in India with HIV and only 49% of the adults with HIV are on ART (1). The HIV infected individuals may require intensive care due to various reasons. This study attempts to look at the outcomes of these patients admitted in the intensive care unit and the predictors of these outcomes. Aims: 1. To assess the outcomes of critically ill HIV infected patients admitted in the medical intensive care unit. 2. Assessment of the factors that are likely to influence the outcome. Materials and Methods: it is a retrospective medical review of all the patient records available on our electronic database. The study period was January 2008 – October 2013. Results: in our study cohort the commonest reason for admission into the intensive care unit was sepsis associated with multi organ dysfunction (64%).A low CD 4 count, renal failure acute respiratory distress syndrome, and hypotension and multi organ dysfunction were predictive of a poor outcome in our study. Conclusion: The most common cause of admission of PLHIV in ours study cohort was Infections, ART associated side effects and low CD4 counts, presence of multi organ dysfunction, acute respiratory distress syndrome (ARDS), hypotension were associated with adverse outcomes.

Keywords

• HIV-positive patients
• intensive care
• mortality outcomes