PLoS ONE (Jan 2014)

Comparing risk of new onset diabetes mellitus in chronic kidney disease patients receiving peritoneal dialysis and hemodialysis using propensity score matching.

  • Che-Yi Chou,
  • Chih-Chia Liang,
  • Huey-Liang Kuo,
  • Chiz-Tzung Chang,
  • Jiung-Hsiun Liu,
  • Hsin-Hung Lin,
  • I-Kuan Wang,
  • Ya-Fei Yang,
  • Chiu-Ching Huang

DOI
https://doi.org/10.1371/journal.pone.0087891
Journal volume & issue
Vol. 9, no. 2
p. e87891

Abstract

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UnlabelledChronic kidney disease (CKD) patients are at risk for developing new-onset diabetes mellitus (NODM) even after hemodialysis (HD) and peritoneal dialysis (PD) treatment. It is not clear if the incidence for NODM is different in CKD patients receiving HD and PD. This study compared the risk of NODM in PD patients and HD patients.MethodsAll HD and PD patients in Taiwan Renal Registry Database from 1997 to 2005 were included and all patients were followed to December 31, 2008. The risk of NODM was analyzed in PD patients and propensity score matched HD patients using logistic regression for early type NODM (6 months after dialysis).ResultsA total of 2548 PD patients and 10192 HD patients who had no diabetes on the initiation of dialysis were analyzed. The incidence for NODM was 3.7 per 100 patient/year for HD and 2.4 for PD patients. HD patients are more at risk for developing early type NODM (pConclusionsChronic kidney disease patients receiving hemodialysis are more at risk for developing new-onset diabetes mellitus compared to those receiving peritoneal dialysis.