Nature Communications (Jul 2017)

Sorting at embryonic boundaries requires high heterotypic interfacial tension

  • Laura Canty,
  • Eleyine Zarour,
  • Leily Kashkooli,
  • Paul François,
  • François Fagotto

DOI
https://doi.org/10.1038/s41467-017-00146-x
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 15

Abstract

Read online

The mechanisms that cause different cells to segregate into distinct tissues are unclear. Here the authors show in Xenopus that formation of a boundary between two tissues is driven by local tension along the interface rather than by global differences in adhesion or cortical contractility.