Hypopigmented mycosis fungoides: Clinical, histological, and immunohistochemical remission induced by narrow-band ultraviolet B

Abstract

Mycosis fungoides (MF) is the most common type of primary cutaneous lymphomas. Several clinical variants of MF have been described. Purely, hypopigmented variant of MF (HMF) is rare. Phototherapy, especially photochemotherapy (Psoralen and ultraviolet), is the most widely used method and is recommended as the first-line treatment for HMF. However, there are no standard guidelines for phototherapy as the disease is uncommon. We, hereby, report a 30-year-old woman with HMF in whom clinical, histopathological, and immunohistochemical remission was achieved following narrow-band ultraviolet B therapy.

Keywords

• Hypopigmented mycosis fungoides
• mycosis fungoides
• narrow-band ultraviolet B
• phototherapy