Effect of interventions of integrated traditional Chinese and Western medicine on chemotherapy-induced gastrointestinal adverse reactions in patients with lung cancer (中西医结合干预对肺癌化疗所致胃肠道反应的影响)

Abstract

Objective To investigate the effect of integrated traditional Chinese and Western medicine on chemotherapy-induced gastrointestinal adverse reaction in patients with lung cancer. Methods Totally 120 lung cancer patients undergoing cisplatin plus irinotecan (IP) were divided into observation group and control group, with 60 cases in each group. All patients received routine preventive measures against gastrointestinal adverse reactions during the chemotherapy, and traditional Chinese medicine appropriate interventions such as auricular point pressing and acupoint application were conducted in the observation group. Degree of gastrointestinal adverse reactions such as nausea and vomiting was evaluated. Results The total effective rate of intervention in the observation group was 91. 67%(55/60), higher than 80. 00%(48/60) in the control group, with a significant difference (P＜0. 05) . Conclusion Interventions of integrated traditional Chinese and Western medicine are potentially effective to reduce the chemotherapy-induced gastrointestinal adverse reactions in patients with lung cancer. (目的 探讨应用中西医结合干预减轻肺癌化疗所致胃肠道反应的效果。方法 120例接受伊立替康联合顺铂(IP)方案治疗的肺癌患者分为观察组和对照组, 各60例。对照组采用常规方案预防化疗所致胃肠道反应, 观察组在对照组基础上增加中医干预方案, 包括耳穴压豆、穴位贴敷等中医适宜技术。观察2组恶心、呕吐发生情况, 评价干预效果。结果 观察组总有效率91. 67%(55/60), 高于对照组的80. 00%(48/60), 差异有统计学意义(P＜0. 05)。结论 中西医结合干预能有效缓解肺癌化疗所致胃肠道反应, 对改善患者化疗期间的生活质量具有积极意义。)

Keywords

• lung cancer
• chemotherapy
• gastrointestinal adverse reactions
• nausea
• vomiting
• integrated traditional chinese and western medicine
• traditional chinese medicine appropriate technique
• 肺癌
• 化疗
• 胃肠道反应
• 恶心
• 呕吐
• 中西医结合
• 中医适宜技术