TOXICOLOGICAL ESTIMATION OF COMBINED ANTITUBERCULAR PREPARATION «PROTUB-2®»

Abstract

Toxicological research of combined antitubercular preparation. «Protub-2®» that contains a pyridoxine hydrochloride (vitamin B). It was established, that introduction of pyridoxine hydrochloride in the structure of preparation «Protub-2®» allowed to reduce the majority of toxic effects caused by isoniazid and rifampicin that are parts of studied, preparation.

Keywords

• antitubercular preparation
• isoniazid
• rifampicin
• pyridoxine hydrochloride (vitamin b₆)
• toxicity
• xanthurenic acid