Nature Communications (Sep 2022)

Endocytosis-like DNA uptake by cell wall-deficient bacteria

  • Renée Kapteijn,
  • Shraddha Shitut,
  • Dennis Aschmann,
  • Le Zhang,
  • Marit de Beer,
  • Deniz Daviran,
  • Rona Roverts,
  • Anat Akiva,
  • Gilles P. van Wezel,
  • Alexander Kros,
  • Dennis Claessen

DOI
https://doi.org/10.1038/s41467-022-33054-w
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 16

Abstract

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Horizontal gene transfer in bacteria can occur through mechanisms such as conjugation, transduction and transformation, which facilitate the passage of DNA across the cell wall. Here, Kapteijn et al. show that cell wall-deficient bacteria can take up DNA and other extracellular materials via an endocytosis-like process.