Data in Brief (Aug 2019)

Data on SVCT2 transporter expression and localization in cancer cell lines and tissues

  • Francisco J. Roa,
  • Eduardo Peña,
  • Eveling Inostroza,
  • Kirsty Sotomayor,
  • Mauricio González,
  • Francisco A. Gutierrez-Castro,
  • Michelle Maurin,
  • Karen Sweet,
  • Claire Labrousse,
  • Marcell Gatica,
  • Carlos F. Aylwin,
  • Pamela Mendoza,
  • Mafalda Maldonado,
  • Carolina Delgado,
  • Jaime Madariaga,
  • Jessica Panes,
  • Tiare Silva-Grecchi,
  • Ilona I. Concha,
  • Gustavo Moraga-Cid,
  • Alejandro M. Reyes,
  • Carola Muñoz-Montesino,
  • Juan Carlos Vera,
  • Coralia I. Rivas

Journal volume & issue
Vol. 25

Abstract

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The data presented in this article are related to the research paper entitled “Increased expression of mitochondrial sodium-coupled ascorbic acid transporter-2 (mitSVCT2) as a central feature in breast cancer”, available in Free Radical Biology and Medicine Journal [1]. In this article, we examined the SVCT2 transporter expression in various breast cancer cell lines using RT-PCR and Western blot assays. In addition, we analyzed the subcellular localization of SVCT2 by immunofluorescence colocalization assays and cellular fractionation experiments. Finally, an analysis of different cancer tissue microarrays immunostained for SVCT2 and imaged by The Human Protein Atlas (https://www.proteinatlas.org) is presented.