Enhanced pupillary light reflex in infancy is associated with autism diagnosis in toddlerhood

Pär Nyström; Teodora Gliga; Elisabeth Nilsson Jobs; Gustaf Gredebäck; Tony Charman; Mark H. Johnson; Sven Bölte; Terje Falck-Ytter

doi:10.1038/s41467-018-03985-4

Nature Communications (May 2018)

Enhanced pupillary light reflex in infancy is associated with autism diagnosis in toddlerhood

Pär Nyström,
Teodora Gliga,
Elisabeth Nilsson Jobs,
Gustaf Gredebäck,
Tony Charman,
Mark H. Johnson,
Sven Bölte,
Terje Falck-Ytter

Affiliations

Pär Nyström: Uppsala Child & Babylab, Department of Psychology, Uppsala University
Teodora Gliga: Centre for Brain and Cognitive Development, Birkbeck, University of London
Elisabeth Nilsson Jobs: Uppsala Child & Babylab, Department of Psychology, Uppsala University
Gustaf Gredebäck: Uppsala Child & Babylab, Department of Psychology, Uppsala University
Tony Charman: Department of Psychology, Institute of Psychiatry, Psychology and Neuroscience, King’s College London
Mark H. Johnson: Centre for Brain and Cognitive Development, Birkbeck, University of London
Sven Bölte: Pediatric Neuropsychiatry Unit, Department of Women’s and Children’s Health, Center of Neurodevelopmental Disorders at Karolinska Institutet (KIND), Karolinska Institutet
Terje Falck-Ytter: Uppsala Child & Babylab, Department of Psychology, Uppsala University

DOI: https://doi.org/10.1038/s41467-018-03985-4
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 5

Abstract

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Previous studies showed that children with autism spectrum disorder (ASD) have atypicalities in the pupillary light reflex (PLR). This study uses longitudinal monitoring of infants at risk for ASD to show that PLR magnitude at 10 months of age is associated with later ASD diagnosis and symptom severity.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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