Nature Communications (Oct 2020)

Shortwave-infrared meso-patterned imaging enables label-free mapping of tissue water and lipid content

  • Yanyu Zhao,
  • Anahita Pilvar,
  • Anup Tank,
  • Hannah Peterson,
  • John Jiang,
  • Jon C. Aster,
  • John Paul Dumas,
  • Mark C. Pierce,
  • Darren Roblyer

DOI
https://doi.org/10.1038/s41467-020-19128-7
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 12

Abstract

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Quantifying lipid and water content in tissues non-invasively is difficult, and no method exists to quantify lipids in blood non-invasively. Here the authors develop an imaging approach called shortwave infrared meso-patterned imaging (SWIR-MPI) to detect and spatially map tissue water and lipids in preclinical models.