INTERRELATION BETWEEN CHITINASE-3-LIKE PROTEIN 1 (CHI3L1) – YKL-40, C-REACTIVE PROTEIN AND SPIROMETRY IN CHRONIC LUNG DISEASE

Abstract

Bronchial asthma is one of the most prevalent chronic diseases in young adults. Numerous studies have investigated the association between genetic variations and expression of different asthma phenotypes, airway hypersensitivity and their inflammation including neutrophilia, eosinophilia and macrophages. Chitinase-3-like protein 1 (CHI3L1) – YKL-40 in serum is a biomarker of inflammation associated with the activity and mortality of lung chronic diseases, diseases that are characterized by inflammation and tissue remodeling. YKL-40 may be an important prognostic biomarker of patients with chronic lung disease.

Keywords

• chitinase-3-like protein 1
• ykl-40
• bronchial asthma
• copd