Impaired renal function in owl monkeys (Aotus nancymai) infected with Plasmodium falciparum

Abstract

Impaired renal function was observed in sixteen Aotus nancymai 25 and 3 months following infection with the Uganda Palo Alto strain of Plasmodium falciparum. Decrease were noted in the clearance of endogenous creatinine, creatinine excretion, and urine volume while increases were observed in serum urea nitrogen, urine protein, urine potassium, fractional excretion of phosphorus and potassium, and activities of urinary enzymes. The results were suggestive of glomerulonephropathy and chronic renal disease.

Keywords

• Aotus nancymai
• Plasmodium falciparum
• impaired renal function
• pathology
• Palo Alto strain