npj Digital Medicine (Jun 2020)
The Project Baseline Health Study: a step towards a broader mission to map human health
- Kristine Arges,
- Themistocles Assimes,
- Vikram Bajaj,
- Suresh Balu,
- Mustafa R. Bashir,
- Laura Beskow,
- Rosalia Blanco,
- Robert Califf,
- Paul Campbell,
- Larry Carin,
- Victoria Christian,
- Scott Cousins,
- Millie Das,
- Marie Dockery,
- Pamela S. Douglas,
- Ashley Dunham,
- Julie Eckstrand,
- Dominik Fleischmann,
- Emily Ford,
- Elizabeth Fraulo,
- John French,
- Sanjiv S. Gambhir,
- Geoffrey S. Ginsburg,
- Robert C. Green,
- Francois Haddad,
- Adrian Hernandez,
- John Hernandez,
- Erich S. Huang,
- Glenn Jaffe,
- Daniel King,
- Lynne H. Koweek,
- Curtis Langlotz,
- Yaping J. Liao,
- Kenneth W. Mahaffey,
- Kelly Marcom,
- William J. Marks,
- David Maron,
- Reid McCabe,
- Shannon McCall,
- Rebecca McCue,
- Jessica Mega,
- David Miller,
- Lawrence H. Muhlbaier,
- Rajan Munshi,
- L. Kristin Newby,
- Ezra Pak-Harvey,
- Bray Patrick-Lake,
- Michael Pencina,
- Eric D. Peterson,
- Fatima Rodriguez,
- Scarlet Shore,
- Svati Shah,
- Steven Shipes,
- George Sledge,
- Susie Spielman,
- Ryan Spitler,
- Terry Schaack,
- Geeta Swamy,
- Martin J. Willemink,
- Charlene A. Wong
Affiliations
- Kristine Arges
- Duke University, School of Medicine
- Themistocles Assimes
- Stanford University, School of Medicine
- Vikram Bajaj
- Stanford University, School of Medicine
- Suresh Balu
- Duke University, School of Medicine
- Mustafa R. Bashir
- Duke University, School of Medicine
- Laura Beskow
- Vanderbilt University, School of Medicine
- Rosalia Blanco
- Duke University, School of Medicine
- Robert Califf
- Verily Inc.
- Paul Campbell
- Duke University, School of Medicine
- Larry Carin
- Duke University, School of Medicine
- Victoria Christian
- Duke University, School of Medicine
- Scott Cousins
- Duke University, School of Medicine
- Millie Das
- Stanford University, School of Medicine
- Marie Dockery
- Duke University, School of Medicine
- Pamela S. Douglas
- Duke University, School of Medicine
- Ashley Dunham
- Duke University, School of Medicine
- Julie Eckstrand
- Duke University, School of Medicine
- Dominik Fleischmann
- Stanford University, School of Medicine
- Emily Ford
- Duke University, School of Medicine
- Elizabeth Fraulo
- Duke University, School of Medicine
- John French
- Duke University, School of Medicine
- Sanjiv S. Gambhir
- Stanford University, School of Medicine
- Geoffrey S. Ginsburg
- Duke University, School of Medicine
- Robert C. Green
- Harvard University, School of Medicine
- Francois Haddad
- Stanford University, School of Medicine
- Adrian Hernandez
- Duke University, School of Medicine
- John Hernandez
- Google Inc.
- Erich S. Huang
- Duke University, School of Medicine
- Glenn Jaffe
- Duke University, School of Medicine
- Daniel King
- Duke University, School of Medicine
- Lynne H. Koweek
- Duke University, School of Medicine
- Curtis Langlotz
- Stanford University, School of Medicine
- Yaping J. Liao
- Stanford University, School of Medicine
- Kenneth W. Mahaffey
- Stanford University, School of Medicine
- Kelly Marcom
- Duke University, School of Medicine
- William J. Marks
- Stanford University, School of Medicine
- David Maron
- Stanford University, School of Medicine
- Reid McCabe
- Duke University, School of Medicine
- Shannon McCall
- Duke University, School of Medicine
- Rebecca McCue
- Stanford University, School of Medicine
- Jessica Mega
- Verily Inc.
- David Miller
- Verily Inc.
- Lawrence H. Muhlbaier
- Duke University, School of Medicine
- Rajan Munshi
- Stanford University, School of Medicine
- L. Kristin Newby
- Duke University, School of Medicine
- Ezra Pak-Harvey
- Duke University, School of Medicine
- Bray Patrick-Lake
- Duke University, School of Medicine
- Michael Pencina
- Duke University, School of Medicine
- Eric D. Peterson
- Duke University, School of Medicine
- Fatima Rodriguez
- Stanford University, School of Medicine
- Scarlet Shore
- Verily Inc.
- Svati Shah
- Duke University, School of Medicine
- Steven Shipes
- Duke University, School of Medicine
- George Sledge
- Stanford University, School of Medicine
- Susie Spielman
- Stanford University, School of Medicine
- Ryan Spitler
- Stanford University, School of Medicine
- Terry Schaack
- California Health and Longevity Institute
- Geeta Swamy
- Duke University, School of Medicine
- Martin J. Willemink
- Stanford University, School of Medicine
- Charlene A. Wong
- Duke University, School of Medicine
- DOI
- https://doi.org/10.1038/s41746-020-0290-y
- Journal volume & issue
-
Vol. 3,
no. 1
pp. 1 – 10
Abstract
Abstract The Project Baseline Health Study (PBHS) was launched to map human health through a comprehensive understanding of both the health of an individual and how it relates to the broader population. The study will contribute to the creation of a biomedical information system that accounts for the highly complex interplay of biological, behavioral, environmental, and social systems. The PBHS is a prospective, multicenter, longitudinal cohort study that aims to enroll thousands of participants with diverse backgrounds who are representative of the entire health spectrum. Enrolled participants will be evaluated serially using clinical, molecular, imaging, sensor, self-reported, behavioral, psychological, environmental, and other health-related measurements. An initial deeply phenotyped cohort will inform the development of a large, expanded virtual cohort. The PBHS will contribute to precision health and medicine by integrating state of the art testing, longitudinal monitoring and participant engagement, and by contributing to the development of an improved platform for data sharing and analysis.
